Starting with version 3.1.61 (released on April 2, 2007), Fashion Master can run under Microsoft Windows Vista (any edition). You do not have to disable the User Account Control to install or run Fashion Master.
In addition, the built-in help will not function until you download and install an update from Microsoft. There are two versions available as a free download: one for 32-bit Windows and one for 64-bit Windows. Most of you will probably have the 32-bit version of Windows. You can download the appropriate file from here: Download Vista Help files. Once installed, Fashion Master's built-in help will be available under Vista.